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Sleep and Performance Research Center Seminar Series
December 13, 2019 @ 11:00 am - 12:00 pm
Dr. Steven Hill will present “Disruption of the Circadian/Melatonin Signal Drives Human Breast Cancer Cells and Xenografts to a Drug-Resistant and Metastatic Phenotype.”
Dr. Hill is a Professor in the Department of Structural & Cellular Biology at Tulane University and the Director of the Tulane Center for Circadian Biology. Dr. Hill’s major fields of interest are breast cancer and circadian biology, including the role of circadian rhythm disruption and the molecular clock in cancer. Dr. Hill’s laboratory recently demonstrated that the pineal hormone melatonin has significant inhibitory effects on the development and growth of human breast cancer. Furthermore, their studies have elucidated that melatonin can potentiate the actions of retinoic acid to induce cell death in human breast tumor cells in culture, to prevent the development of carcinogen-induced breast cancer in rats and to induce the regression of over 70% of established breast tumors in rats. These studies are currently being moved into human clinical trials. Find more information on his website (here).
Everyone is invited.