{"id":1758,"date":"2016-03-17T19:18:27","date_gmt":"2016-03-17T19:18:27","guid":{"rendered":"https:\/\/spokane.wsu.edu\/extra\/?p=1758"},"modified":"2016-03-17T21:57:11","modified_gmt":"2016-03-17T21:57:11","slug":"wsu-college-pharmacy-fights-als-alzheimers","status":"publish","type":"post","link":"https:\/\/spokane.wsu.edu\/news\/research\/wsu-college-pharmacy-fights-als-alzheimers\/","title":{"rendered":"WSU College of Pharmacy fights ALS, Alzheimer&#8217;s and more"},"content":{"rendered":"<p class=\"p1\"><a href=\"https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros.jpg\" rel=\"attachment wp-att-1764\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone wp-image-1764\" src=\"https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros-396x264.jpg\" alt=\"WSU College of Pharmacy research\" width=\"528\" height=\"352\" srcset=\"https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros-396x264.jpg 396w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros-768x512.jpg 768w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros-792x528.jpg 792w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros-990x660.jpg 990w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Denton-Travis-Pharm-Sci2-Cori-Medeiros-1188x792.jpg 1188w\" sizes=\"(max-width: 528px) 100vw, 528px\" \/><\/a><\/p>\n<p class=\"p1\"><em>&#8220;Right here in Spokane, Washington, we could potentially be making the drug to give to people with ALS that could stop their complications altogether.&#8221;<\/em><\/p>\n<p class=\"p1\">Those are the words of <a href=\"http:\/\/www.pharmacy.wsu.edu\/facultystaff\/bios\/denton.t.html\" target=\"_blank\">Travis Denton<\/a>, a medicinal chemist in the <a href=\"http:\/\/www.pharmacy.wsu.edu\/?utm_source=spokane-wsu-edu&amp;utm_medium=online&amp;utm_campaign=spokane-wsu-edu-%28direct%29&amp;utm_term=&amp;utm_content=\" target=\"_blank\">WSU College of Pharmacy<\/a>. Denton is trying to find a drug that <a href=\"https:\/\/news.wsu.edu\/2016\/03\/16\/wsu-searches-drugs-fight-als-alzheimers-brain-disorders\/\" target=\"_blank\">could repair the brain&#8217;s &#8220;house-cleaning function&#8221;<\/a> and help those suffering from ALS, Alzheimer&#8217;s, Parkinson&#8217;s and more.<\/p>\n<p class=\"p1\"><!--more--><a href=\"https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Travis-Denton.jpg\" rel=\"attachment wp-att-1766\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft wp-image-1766\" src=\"https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Travis-Denton-396x479.jpg\" alt=\"Travis Denton\" width=\"150\" height=\"182\" srcset=\"https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Travis-Denton-396x479.jpg 396w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Travis-Denton-768x930.jpg 768w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Travis-Denton-792x959.jpg 792w, https:\/\/wpcdn.web.wsu.edu\/wp-spokane\/uploads\/sites\/456\/2016\/03\/Travis-Denton.jpg 826w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/a><a href=\"http:\/\/www.krem.com\/news\/local\/2-on-your-side\/breakthrough-in-als-research-could-come-from-wsu-spokane\/85408217\" target=\"_blank\">Denton shared his work with KREM2<\/a>.<\/p>\n<p class=\"p1\">Denton (left) is working with <a href=\"https:\/\/www.utoledo.edu\/med\/depts\/path\/Hensley.html\" target=\"_blank\">Dr. Kenneth Hensley<\/a> of the University of Toledo to look at the brain&#8217;s autophagy process &#8211; the process that cleans old or damaged particles and protein from brain cells (the &#8220;house-cleaning function&#8221;). Denton received $446,233 over three years from the <a href=\"http:\/\/www.ninds.nih.gov\/\" target=\"_blank\">National Institutes of Neurological Disorders and Stroke<\/a> to help fund his study and hopeful development of a new drug.<\/p>\n<p class=\"p1\">The autophagy process doesn&#8217;t work properly for those suffering from ALS, Alzheimer&#8217;s and other brain maladies. Hensley has found a new way to activate the autophagy process, and he and Denton will conduct studies to hopefully discover ways it can work in the brain.<\/p>\n<p class=\"p1\">This is another example of researches on our campus <a href=\"https:\/\/spokane.wsu.edu\/extra\/2015\/05\/15\/research-is-a-problem-solver\/\">solving problems<\/a> and addressing complex health issues in our society.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Right here in Spokane, Washington, we could potentially be making the drug to give to people with ALS that could stop their complications altogether.&#8221; Those are the words of Travis [&hellip;]<\/p>\n","protected":false},"author":[],"featured_media":1764,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[437],"tags":[1161,551,447],"wsuwp_university_location":[],"wsuwp_university_org":[],"_links":{"self":[{"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/posts\/1758"}],"collection":[{"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/users\/528"}],"replies":[{"embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/comments?post=1758"}],"version-history":[{"count":16,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/posts\/1758\/revisions"}],"predecessor-version":[{"id":1776,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/posts\/1758\/revisions\/1776"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/media\/1764"}],"wp:attachment":[{"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/media?parent=1758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/categories?post=1758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/tags?post=1758"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/author?post=1758"},{"taxonomy":"wsuwp_university_location","embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/wsuwp_university_location?post=1758"},{"taxonomy":"wsuwp_university_org","embeddable":true,"href":"https:\/\/spokane.wsu.edu\/news\/wp-json\/wp\/v2\/wsuwp_university_org?post=1758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}