Nuclear Magnetic Resonance (NMR) is an extremely powerful technique for investigating the structure of chemical species, primarily those in solution, by the radio-frequency interrogation of the sample held in a powerful magnetic field.
There is a variety of application in many disciplines of scientific research. NMR has been extensively used in drug screening and lead identification. In addition, NMR experiments can be designed to probe phenomena including molecular geometry, binding between molecules (for example drug candidate binding to biomolecules). Together with X-ray crystallography, NMR spectroscopy is one of the two leading technologies for the structure determination of biomolecules at atomic resolution.
Bruker Avance I 500 MHz NMR
Presently, we have a Bruker Avance I 500 MHz NMR with an inverse triple resonance auto-tuned probe (5 mm) for observation of 1H, 13C and 19F and an additional manually tuned probe (5 mm) for observation of 31P. We can routinely offer 1D-dimensional NMR spectra of 1H, 13C, 19F and 31P and a range of 2D-dimensional NMR spectra, such as COSY, HMBC, HSQC, for the molecular structure analysis.
Our primary objective is to support the research activities in WSU at Spokane. We also aim to offer a flexible and responsive service to other academic institutions and industries where possible. The NMR Core Facility of WSU at Spokane is located in the Center for Clinical Research and Simulation (formerly the South Campus Facility).