{"id":8226,"date":"2025-04-16T12:02:39","date_gmt":"2025-04-16T19:02:39","guid":{"rendered":"https:\/\/spokane.wsu.edu\/research\/?page_id=8226"},"modified":"2025-11-19T12:35:31","modified_gmt":"2025-11-19T20:35:31","slug":"proteomics-metabolomics-service-center","status":"publish","type":"page","link":"https:\/\/spokane.wsu.edu\/research\/research-service-centers\/proteomics-metabolomics-service-center\/","title":{"rendered":"Proteomics and Metabolomics Service Center"},"content":{"rendered":"
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Proteomics\/Metabolomics Service Center <\/h2>\n\n\n\n

The Proteomics\/Metabolomics Service Center is fully equipped to support diverse research needs across Washington State University, other academic institutions, and industry partners. Utilizing state-of-the-art instrumentation, such as the Orbitrap Q Exactive HF mass spectrometer from Thermo Fisher Scientific and advanced nano-LC systems, the system provides high-quality data. With a focus on both standard and specialized services, coupled with robust training and collaborative support, our center enables researchers to push the boundaries of proteomics research.<\/p>\n\n\n\n

Common Proteomics Services Offered:<\/h2>\n\n\n
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Protein Identification and Characterization<\/h3>\n\n\n\n
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  • Bottom-up proteomics for comprehensive protein identification<\/li>\n\n\n\n
  • Top-down proteomics for intact protein analysis<\/li>\n<\/ul>\n\n\n\n

    Quantitative Proteomics<\/h3>\n\n\n\n
      \n
    • Label-free quantitation (LFQ) for relative protein abundance<\/li>\n\n\n\n
    • Isobaric tagging (TMT\/iTRAQ) for multiplexed quantitation<\/li>\n\n\n\n
    • Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)<\/li>\n\n\n\n
    • Targeted quantitation using Parallel Reaction Monitoring (PRM)<\/li>\n<\/ul>\n\n\n\n

      Post-Translational Modification (PTM) Analysis<\/h3>\n\n\n\n
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      • Phosphorylation site mapping and quantitation<\/li>\n\n\n\n
      • Acetylation profiling<\/li>\n\n\n\n
      • Glycosylation characterization<\/li>\n<\/ul>\n\n<\/div>\r\n\n\n
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        Protein-Protein Interaction Studies<\/h3>\n\n\n\n
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        • Co-immunoprecipitation (Co-IP) coupled with MS analysis<\/li>\n\n\n\n
        • Cross-linking Mass Spectrometry (XL-MS)<\/li>\n<\/ul>\n\n\n\n

          Metabolomics Study<\/h3>\n\n\n\n
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          • Targeted and untargeted LC\/MS<\/li>\n<\/ul>\n\n\n\n

            Sample Preparation and Method Development<\/h3>\n\n\n\n
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            • Custom sample preparation protocols for challenging samples<\/li>\n\n\n\n
            • Development and optimization of LC-MS\/MS methods tailored to specific research needs<\/li>\n<\/ul>\n\n\n\n

              Collaborative Research Support<\/h3>\n\n\n\n
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              • Assistance with grant writing for proteomics projects<\/li>\n\n\n\n
              • Experimental design consultation<\/li>\n\n\n\n
              • Manuscript preparation support for proteomics data<\/li>\n\n\n\n
              • Collaborative projects with Service Center staff<\/li>\n<\/ul>\n\n<\/div>\r\n\n<\/div>\n\n\n

                Flexible Access and Pricing Models<\/h2>\n\n\n\n

                The Proteomics and Metabolomics Service Center offers flexible access and pricing models to cater to various research needs:<\/p>\n\n\n\n

                  \n
                • Rates per sample for routine proteomic or metabolomic analysis.<\/li>\n<\/ul>\n\n\n\n

                  Full Service<\/h3>\n\n\n\n
                  Number of samples<\/th>Cost (WSU)<\/th>Cost (Non-WSU)<\/th><\/tr><\/thead>
                  1-5<\/td>$400<\/td>$540<\/td><\/tr>
                  6-10<\/td>$350<\/td>$470<\/td><\/tr>
                  11-20<\/td>$280<\/td>$380<\/td><\/tr>
                  >20<\/td>$220<\/td>$300<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n
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                  Full-service includes peptide digestion LC-MS run and data analysis. Sample must be submitted as a batch to get bulk discounts.<\/p>\n\n<\/div>\n\n\n\n

                  LC-MS + Analysis<\/h3>\n\n\n\n
                  Number of samples<\/th>Cost (WSU)<\/th>Cost (Non-WSU)<\/th><\/tr><\/thead>
                  1-5<\/td>$320<\/td>$430<\/td><\/tr>
                  6-10<\/td>$240<\/td>$325<\/td><\/tr>
                  11-20<\/td>$205<\/td>$275<\/td><\/tr>
                  >20<\/td>$160<\/td>$215<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

                  LC-MS (Run Only)<\/h3>\n\n\n\n
                  Number of samples<\/th>Cost (WSU)<\/th>Cost (Non-WSU)<\/th><\/tr><\/thead>
                  1-5<\/td>$280<\/td>$380<\/td><\/tr>
                  6-10<\/td>$205<\/td>$275<\/td><\/tr>
                  11-20<\/td>$185<\/td>$250<\/td><\/tr>
                  >20<\/td>$135<\/td>$180<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

                  Contact Us<\/h2>\n\n\n\n

                  Many projects will involve more than just routine services and may include method development, additional sample pretreatment, data analysis, and more. For more information and questions around pricing, contact Dr. John Clarke<\/strong> (j.clarke@wsu.edu) and Dr. Eileen Yue<\/strong> (Guihua.yue@wsu.edu).<\/p>\n\n\n

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