Past Feature Stories
Protein discovery could help prevent cancer treatment-related heart damage
May 2024
Blocking a protein known as CDK7 could prevent heart damage associated with a commonly used cancer chemotherapy medication, according to a study led by scientists at Washington State University. Importantly, the researchers also found that inhibiting CDK7 could help enhance the medication’s cancer-killing capability.
Based on an animal model, the study findings could provide a foundation for future treatment strategies to reduce chemotherapy-related heart toxicity and increase treatment effectiveness. This could ultimately help increase the lifespan of people with cancer.
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Blood sugar lows and highs hamper brain function in type 1 diabetes
March 2024
Large swings in blood glucose tied to Type 1 diabetes may impact the brain’s ability to quickly process information, according to a study led by scientists at Washington State University and McLean Hospital in Massachusetts. The research also showed that some individuals are more severely impacted by these changes, which includes older people and those with certain health conditions.
Published in npj Digital Medicine, the study found that very low and very high glucose levels were associated with slower and less accurate cognitive processing speed, with the most dramatic effect seen at low glucose levels.
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WSU team to study care of babies exposed to drugs
January 2024
As overdose deaths from fentanyl are soaring across the nation, researchers at Washington State University Spokane are focusing on a new way to help the youngest victims of the opioid crisis—babies going through substance withdrawal after being exposed before birth, a condition known as neonatal abstinence syndrome. As part of a state-supported pilot project, a team of researchers in the WSU colleges of nursing and medicine will spend the next year studying health outcomes at Maddie’s Place, a newly opened, Spokane-based transitional care nursery that provides care and support for drug-exposed babies and moms.
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New lab to test home health technologies, train tech-savvy nurses
October 2023
A new Washington State University laboratory focused on home health technologies could potentially improve health outcomes and quality of life for adults with chronic conditions.
Led by nurse scientists, the Nurse Technology Enhanced Care at Home (NTECH) lab will test off-the-shelf health innovations and develop new technologies to manage chronic conditions at home. Down the line, it will also provide a training ground for aspiring nurse scientists looking to enter the health technology field.
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WSU helps state pilot new substance use treatment
August 2023
Substance use research at Washington State University helped spur a recent change in Washington state policy to provide Medicaid coverage for contingency management, a behavioral treatment that uses gift cards and small prizes to help motivate people to quit using drugs. WSU researchers, who have been conducting studies that show contingency management’s effectiveness for decades, have spent the past two years providing training and coaching to a small number of Washington state clinics implementing the intervention to treat stimulant drug addiction as part of a pilot project sponsored by the state Health Care Authority.
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Research Addresses Mental Health, Substance Use in Supportive Housing
May 2023
As cities across the state and country are struggling to deal with a worsening homelessness crisis, a group of WSU scientists is helping to improve outcomes for people in permanent supportive housing. Working with housing providers in Spokane, Seattle, and Los Angeles, researchers in the Promoting Research Initiatives in Substance Use and Mental Health (PRISM) Collaborative are leading projects aimed at addressing homelessness.
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Comparison with Canada highlights poor access to US methadone treatment
March 2023
People living in the United States must travel significantly farther to access methadone treatment for opioid addiction than Canadians, suggests a new study led by Washington State University researchers. The researchers’ analysis showed that the average driving distance to the closest methadone clinic accepting new patients was more than three times greater in the U.S. compared to Canada. When limiting their analysis to clinics that could provide treatment within 48 hours the difference was even larger, with those in the U.S. having to travel more than five times farther than their neighbors north of the border.
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Ensuring drug safety in underrepresented populations
January 2023
Washington State University scientists are helping to develop safer drug dosing standards for children and other populations that are underrepresented in clinical drug trials, such as pregnant women, older adults taking multiple medications, and people from certain ethnic groups. Bhagwat Prasad, an associate professor in the College of Pharmacy and Pharmaceutical Sciences, is leading the research, which could help pharmaceutical companies and medical professionals determine the right dosing for many drugs prescribed to children that have only ever been tested in adults.
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Twin research sheds light on how lifestyle, environment impact health
October 2022
Many people’s best ideas may come in the shower, but for Dedra Buchwald—director of the WSU Institute for Research and Education to Advance Community Health—one stroke of research genius hit her at her local driver’s licensing office almost 25 years ago. A professor of medicine at the University of Washington at the time, Buchwald had gone in to replace a lost driver’s license. While filling out a form, a question caught her eye: “Are you a twin or a triplet?”
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Researcher spearheads new way to screen kids for autism
August 2022
Measuring how the eyes’ pupils change in response to light—known as the pupillary light reflex—could potentially be used to screen for autism in young children, according to a study conducted at Washington State University. First author Georgina Lynch said the proof-of-concept study builds on earlier work to support the continued development of a portable technology that could provide a quick and easy way to screen children for autism, a disorder that affects communication and social interaction with others.
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Native Americans face disproportionate travel burden for cancer treatment
June 2022
Experiencing higher rates of certain cancers than non-Hispanic whites, many Native Americans have to travel especially large distances to access radiation therapy, according to a study led by Washington State University researchers. Published in the journal Value in Health, the study found that individuals living in U.S. neighborhoods with majority American Indian and Alaska Native populations have to travel around 40 miles farther to the nearest radiation therapy facility than those living in neighborhoods dominated by other racial groups.
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Hyperbaric oxygen therapy shows promise for opioid addiction treatment
April 2022
Hyperbaric oxygen therapy may help people being treated for opioid addiction reduce their methadone dose and better manage pain and withdrawal symptoms, according to a pair of studies led by Washington State University scientists.
The research team recruited participants enrolled in a local opioid treatment program to test the effects of hyperbaric oxygen therapy, a treatment that involves breathing pure oxygen in a pressurized environment.
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Discovery could help finetune immunity to fight infections, disease
February 2022
Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with can respond differently to specific pathogens. This quality, known as immunological specificity, was previously ascribed only to the adaptive immune system, which develops over time through disease exposure.
Published in the journal Cell Reports, the study suggests that this innate immune specificity is driven by the nervous system and identifies a neuronal protein as a critical link in the process.
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Cannabis use could cause harmful drug interactions
December 2021
Using cannabis alongside other drugs may come with a significant risk of harmful drug-drug interactions, new research by scientists at Washington State University suggests.
The researchers looked at cannabinoids—a group of substances found in the cannabis plant—and their major metabolites found in cannabis users’ blood and found that they interfere with two families of enzymes that help metabolize a wide range of drugs prescribed for a variety of conditions.
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Research helps tackle health barriers for people with disabilities
October 2021
About one in every four U.S. adults lives with a disability. Adding up to an estimated 61 million Americans, people with disabilities are easily the largest minority in the nation. Yet their minority status isn’t always recognized to the extent it should be, said Jae Kennedy, a professor in the Elson S. Floyd College of Medicine who has spent the past 30 years studying how public policy affects those with disabilities.
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Research identifies potential role of ‘junk DNA’ in aging, cancer
July 2021
The human body is essentially made up of trillions of living cells. It ages as its cells age, which happens when those cells eventually stop replicating and dividing. Scientists have long known that genes influence how cells age and how long humans live, but how that works exactly remains unclear. Findings from a new study led by researchers at Washington State University have solved a small piece of that puzzle, bringing scientists one step closer to solving the mystery of aging.
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